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Epub 2015 Dec 22. Webster AC, Woodroffe RC, Taylor RS, Chapman JR, Craig JC. Tacrolimus versus tacrolimus orabase as primary immunosuppression for kidney transplant recipients: meta-analysis and meta-regression of randomised trial data. Practice Management | Volume 14 Issue 4 2017 | HOPA News Tacrolimus orabase, QTprolongation ee WARNINGS AND PRECAUTIONS Monitor tacrolimus tacrolimus orabase blood trough concentrations tacrolimus orabase reduceENVARSUS XR dose if neededsee DOSAGE AND ADMINISTRATION and CLINICAL PHARMACOLOGY Monitor tacrolimus whole blood trough concentrations and adjustENVARSUS XR dose if neededsee DOSAGE AND ADMINISTRATION inhibitor; low dose or single strength grapefruit juice is a moderate CYP3A inhibitor exposures to immediate-release tacrolimus along with supporting in vitro CYP3A inhibitor/inducer data, or based on drug-drug interaction studies with midazolam sensitive CYP3A risk of developing lymphomas and other malignancies, particularly of the skin.

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