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Sztajnkrycer MD, Bond GR, Johnson SB, Weaver AL. Use of vasopressin in a canine model of severe verapamil poisoning: a preliminary descriptive study. Acad Emerg Med. 2004 Dec. 53-61.Ther Apher Dial. 2008 Apr. -4.

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The therapeutic benefits of diltiazem in supraventricular tachycardias are related to its ability to slow AV nodal conduction time and prolong AV nodal refractoriness. Diltiazem exhibits frequency use best time of day to take cardizem effects on AV nodal conduction such that it may selectively reduce the heart rate during tachycardias involving the AV node with little or no effect on normal AV nodal conduction at normal heart rates.Benson BE, Spyker DA, Troutman WG, Watson WA, Bakhireva LN.

Amlodipine toxicity in children less than 6 years of age: a dose-response analysis using national poison data system data. J Emerg Med. 2010 Aug. -93.

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Sixteen of these reports involved multiple drug ingestions. Twenty-two reports indicated patients had recovered from diltiazem overdose ranging from less than 1 g to 10.ultum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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Apart from its main FDA-approved indications, diltiazem has also been used for numerous off-label indications, such as anal fissures in topical formulations migraine prophylaxis, pulmonary hypertension, and rest-related cramps in the lower extremities.It should not be used to treat angina when it occurs.

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